Acetylcysteine 200mg/ml 10x10ml ampoules are indicated for the treatment of paracetamol overdose in patients:

a) who have taken a staggered overdose irrespective of plasma paracetamol level. Staggered is defined as an overdose where the paracetamol was ingested over a period of 1 hour or more; or

b) where there is any doubt over the time of the overdose, irrespective of plasma paracetamol level; or

c) who present with a plasma paracetamol level on or above a line joining points of 100mg/L at 4h and 15mg/L at 15h.